Sulfonylurea challenge test in subjects diagnosed with type 1 diabetes mellitus

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The challenge of type 1 diabetes mellitus.

Diabetes mellitus is a heterogeneous group of diseases characterized by high blood glucose levels due to defects in insulin secretion, insulin action, or both. With the number of cases expected to increase rapidly in the years to come, diabetes is a growing health challenge worldwide. Of the approximately 16 million diabetics in the United States, about 1.5 million suffer from type 1 diabetes. ...

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Initial Sulfonylurea Use and Subsequent Insulin Therapy in Older Subjects with Type 2 Diabetes Mellitus

BACKGROUND In type 2 diabetes mellitus (T2DM), progressive loss of beta cell function over time requires treatment intensification and eventually initiation of insulin for many patients. Relative to metformin, a greater rate of decline in beta cell function over time has been observed with sulfonylurea treatment. The present study examined the association between initial monotherapy with metfor...

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PLASMA DEHYDROASCORBIC ACID LEVELS IN IRANIAN SUBJECTS WITH DIABETES MELLITUS

Several reports concerning high plasma dehydroascorbic acid (DHAsA) levels in diabetics have been published and from these reports, suggestions that monitoring of DHAsA levels in those persons with a predisposition to diabetes mellitus would be of value. However, conflicting reports have also appeared which do not confirm high levels of DHAsA in diabetic subjects when compared to controls....

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Clinical Characteristics of Subjects with Sulfonylurea-Dependent Type 2 Diabetes

BACKGROUND Even though several oral anti-diabetic drugs (OAD) with various modes of action are replacing sulfonylurea (SU), some patients seem to be dependent on SU for adequate glycemic control. Therefore, we evaluated the clinical characteristics of such patients. METHODS We selected the patients with type 2 diabetes who met following criteria from 2009 to 2014 at Seoul National University ...

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ژورنال

عنوان ژورنال: Pediatric Diabetes

سال: 2017

ISSN: 1399-543X

DOI: 10.1111/pedi.12489